Aldosterone, Vascular Endothelial Growth Factor, and Preeclampsia
نویسندگان
چکیده
منابع مشابه
Aldosterone, vascular endothelial growth factor, and preeclampsia: a mystery solved?
T he renin–angiotensin system (RAS) is one of the key players in volume and sodium homeostasis. Activation of the RAS leads to vasoconstriction, sodium retention, and volume expansion via the action of angiotensin II and the effector hormone of the RAS, aldosterone. The RAS can also respond to changes in plasma volume; activation of the RAS is seen in states of volume contraction and will lead ...
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Aldosterone levels are markedly elevated during normal pregnancy but fall even though volume contracts when preeclampsia occurs. The level of aldosterone in either condition cannot be explained solely by the activity of the renin-angiotensin II system. In normal gestation, vascular endothelial growth factor (VEGF) is thought to maintain vascular health, but its role in adrenal hormone productio...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2013
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.111.00767